January 17, 2019
+91-44-24618817, 24616948
Faculty Member


Makesh, M. Dr.

Principal Scientist
Discipline: Veterinary Microbiology
Division: Finfish Culture Division
Specialization: Fish Immunology

Contact Me

Phone: +91- 044 – 24618817 Ext:431
Fax: +91- 044 – 24610311

Brief profile:

After taking masters in Veterinary Microbiology in 1997 and PhD in Veterinary Microbiology in 2005 I am working in CIBA since April 2015 on fish breeding and larval rearing. I currently work in division of Fish Culture in CIBA. I have worked on fish immunology and have contributed to development of immunodiagnostics for fish and shellfish diseases. I have interests in mucosal immunity and application of probiotics for larval rearing.

Research areas:

  • Fish immunology
  • Fish disease diagnostics
  • Larval rearing

Current Research Projects:

Funded By
1 ICAR All India Network Project on Fish Health ICAR
2 Biotechnological interventions and application of bioinformatic tools for improvement of brackishwater fish and shellfish Institute

DBT-CREST Award 2012

Best 5 Publications during the Career


  • Makesh, M., Koteeswaran, A., Chandran, N. Daniel Joy, Manohar, B. Murali, Ramasamy, V., 2006. Development of monoclonal antibodies against VP28 of WSSV and its application to detect WSSV using immunocomb. Aquaculture, 261:64-71.
  • Manas Ranjan Bag, M. Makesh, K.V. Rajendran, S.C. Mukherjee. 2009. Characterization of IgM of Indian major carps and their cross- reactivity with anti-fish IgM antibodies. Fish and shellfish Immunology. 26:275-278.
  • Brajendu Kumar, A. Deepika, M. Makesh, C. S. Purushothaman, K. V. Rajendran. 2012. Production and characterization of monoclonal antibodies to the hemocytes of mud crab, Scylla serrata. Journal of Invertebrate Pathology 111: 86–89.
  • Deepika A, M. Makesh and K.V. Rajendran (2014). Development of primary cell cultures from mud crab, Scylla serrata, and their potential as an in vitro model for replication of white spot syndrome virus. In vitro cell and developmental biology-animal 50:406-416.
  • Pushpa K, P. Gireesh-Babu, K. V. Rajendran, C. S. Purushothaman, S. Dasgupta, M. Makesh. 2014. Molecular cloning, sequencing and tissue-level expression of complement C3 of Labeo rohita (Hamilton, 1822). Fish and Shellfish Immunology 40: 319-330


Best 3 Publications during last 3 years


  1. Makesh M, Ponnerassery S. Sudheesh, Kenneth D. Cain. 2015. Systemic and mucosal immune response of rainbow trout to immunization with an attenuated Flavobacterium psychrophilum vaccine strain by different routes. Fish & Shellfish Immunology, 44; 156-163.
  2. Parhi J, Mukherjee SC, Saxena G, Sahoo L, Makesh M. 2014. Molecular characterization and expression of type-I interferon gene in Labeo rohita. Molecular Biology Reports 41:2979-2987.
  3. Sajad Ahanger, Supriyanka Sandaka, Deepika Ananad, Madhu K. Mani, Ravinder Kondadhasula, Chandra Sekhar Reddy, Makesh Marappan, Rajendran K. Valappil, Kshitish C. Majumdar and Rakesh K. Mishra. 2014. Protection of Shrimp Penaeus monodon from WSSV Infection Using Antisense Constructs. Mar. Biotechnol. 16:63–73